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zadetkov: 80
31.
  • Dapper-1 is essential for W... Dapper-1 is essential for Wnt5a induced cardiomyocyte hypertrophy by regulating the Wnt/PCP pathway
    Hagenmueller, Marco; Riffel, Johannes H; Bernhold, Elmar ... FEBS letters, 06/2014, Letnik: 588, Številka: 14
    Journal Article
    Recenzirano
    Odprti dostop

    •Wnt5a stimulation induces cardiomyocyte hypertrophy.•Knockdown of Dpr1 blocks Wnt5a induced cardiomyocyte hypertrophy.•Dpr1 is required for Wnt5a mediated activation of JNK.•Dpr1 depletion leads to ...
Celotno besedilo
32.
  • Osthole ameliorates acute m... Osthole ameliorates acute myocardial infarction in rats by decreasing the expression of inflammatory-related cytokines, diminishing MMP-2 expression and activating p-ERK
    Duan, Juan; Yang, Yu; Liu, Hong ... International journal of molecular medicine 37, Številka: 1
    Journal Article, Publication
    Recenzirano
    Odprti dostop

    Osthole, the active constituent of Cnidium monnieri extracts, has been shown to have a diverse range of pharmacological properties. In the present study, we aimed to evaluate the cardioprotective ...
Celotno besedilo
33.
  • Redefining the roles of p38... Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: dichotomy between cultured myocytes and animal models
    Liang, Qiangrong; Molkentin, Jeffery D Journal of Molecular and Cellular Cardiology, 2003, 2003-Dec, 2003-12-00, 20031201, Letnik: 35, Številka: 12
    Book Review, Journal Article
    Recenzirano

    The mitogen-activated protein kinase (MAPK) signaling pathways serve as pivotal transducers of diverse biologic functions including cell growth, differentiation, proliferation, and apoptosis. The ...
Celotno besedilo
34.
  • A Genome-Wide Screen Reveal... A Genome-Wide Screen Reveals a Role for microRNA-1 in Modulating Cardiac Cell Polarity
    King, Isabelle N; Qian, Li; Liang, Jianping ... Developmental cell, 04/2011, Letnik: 20, Številka: 4
    Journal Article
    Recenzirano
    Odprti dostop

    Many molecular pathways involved in heart disease have their roots in evolutionarily ancient developmental programs that depend critically on gene dosage and timing. MicroRNAs (miRNAs) modulate gene ...
Celotno besedilo
35.
  • Mitogen-activated protein k... Mitogen-activated protein kinase phosphatase-1: a critical phosphatase manipulating mitogen-activated protein kinase signaling in cardiovascular disease (review)
    Li, Chang-Yi; Yang, Ling-Chao; Guo, Kai ... International journal of molecular medicine 35, Številka: 4
    Journal Article
    Recenzirano
    Odprti dostop

    Mitogen-activated protein kinase (MAPK) cascades are important players in the overall representation of cellular signal transduction pathways, and the deregulation of MAPKs is involved in a variety ...
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36.
  • Isoproterenol induced hyper... Isoproterenol induced hypertrophy and associated signaling pathways are modulated by Somatostatin in H9c2 cells
    Somvanshi, Rishi K; Qiu, Xiaofan; Kumar, Ujendra International journal of cardiology, 2012, 2013-08-10, 2013, 2013-Aug-10, 2013-08-00, 20130810, Letnik: 167, Številka: 3
    Journal Article
    Recenzirano

    Abstract Background Somatostatin (SST), a growth hormone inhibitory peptide plays key role in regulation of cell proliferation via modulation of mitogen activated protein kinases (MAPKs) and cell ...
Celotno besedilo
37.
  • Smad3 and Extracellular Sig... Smad3 and Extracellular Signal-Regulated Kinase 1/2 Coordinately Mediate Transforming Growth Factor-β-Induced Expression of Connective Tissue Growth Factor in Human Fibroblasts
    Leivonen, Suvi-Katri; Häkkinen, Lari; Liu, David ... Journal of investigative dermatology, June 2005, 2005-06-00, 2005, 2005-Jun, 20050601, 2005-06-01, Letnik: 124, Številka: 6
    Journal Article
    Recenzirano
    Odprti dostop

    Connective tissue growth factor (CTGF) is secreted by fibroblasts stimulated with transforming growth factor-β (TGF-β). CTGF is a potent enhancer of fibroblast proliferation, chemotaxis, and ...
Celotno besedilo
38.
  • Molecular mechanisms of apo... Molecular mechanisms of apoptosis in the cardiac myocyte
    Bishopric, Nanette H; Andreka, Peter; Slepak, Tatiana ... Current Opinion in Pharmacology, 2001, 2001-Apr, 2001-04-01, 20010401, Letnik: 1, Številka: 2
    Book Review, Journal Article
    Recenzirano

    Cardiac myocytes can undergo programmed cell death in response to a variety of insults and apoptotic elimination of myocytes from the adult myocardium can lead directly to cardiomyopathy and death. ...
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39.
  • PTPN11 -Associated Mutation... PTPN11 -Associated Mutations in the Heart: Has LEOPARD Changed Its RASpots?
    Lauriol, Jessica; Kontaridis, Maria I Trends in cardiovascular medicine, 2011, May 2011, 2011-May, 2011-05-00, 20110501, 2011-05-01, 20110500, Letnik: 21, Številka: 4
    Journal Article, Publication
    Recenzirano
    Odprti dostop

    In this review, we focus on elucidating the cardiac function of germline mutations in the PTPN11 gene, encoding the Src homology-2 (SH2) domain–containing protein tyrosine phosphatase SHP2. PTPN11 ...
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40.
  • Mechanical stress-initiated... Mechanical stress-initiated signal transductions in vascular smooth muscle cells
    Li, Chaohong; Xu, Qingbo Cellular Signalling, 2000, 2000-Jul, 2000-07-00, 20000701, Letnik: 12, Številka: 7
    Book Review, Journal Article
    Recenzirano

    Mechanical force is an important modulator of cellular morphology and function in a variety of tissues, and is particularly important in cardiovascular systems. Vascular smooth muscle cell (VSMC) ...
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