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3 4 5 6 7
zadetkov: 80
41.
  • Activation of AP-1 through ... Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes
    Wu, Shuling; Gao, Jianping; Ohlemeyer, Carsten ... Free radical biology & medicine, 2005, 2005-Dec-15, 2005-12-15, 20051215, Letnik: 39, Številka: 12
    Journal Article
    Recenzirano

    Cardiovascular pathogenesis induced by angiotensin II (Ang-II) is a complex process often connected to oxidative stress. In the present study we show that, 4 h after addition, Ang-II induces a four- ...
Celotno besedilo
42.
  • TACE is required for fetal ... TACE is required for fetal murine cardiac development and modeling
    Shi, Wei; Chen, Hui; Sun, Jianping ... Developmental biology, 2003, 2003-Sep-15, 2003-09-00, 20030915, 2003-09-01, Letnik: 261, Številka: 2
    Journal Article
    Recenzirano
    Odprti dostop

    Tumor necrosis factor-α converting enzyme (TACE) is a membrane-anchored, Zn-dependent metalloprotease, which belongs to the ADAM (a disintegrin and metalloprotease) family. TACE functions as a ...
Celotno besedilo
43.
  • Stress-Activated MAP Kinase... Stress-Activated MAP Kinases in Cardiac Remodeling and Heart Failure: New Insights from Transgenic Studies
    Petrich, Brian G; Wang, Yibin Trends in cardiovascular medicine, 2004, 2004-Feb, 2004-02-00, 20040201, Letnik: 14, Številka: 2
    Journal Article
    Recenzirano

    Activation of stress-activated mitogen-activated protein kinases (SAPKs), mainly c-Jun N-terminal kinase (JNK) and p38, have long been associated with different forms of cardiac pathology across a ...
Celotno besedilo
44.
  • Stretch-induced regulation ... Stretch-induced regulation of angiotensinogen gene expression in cardiac myocytes and fibroblasts: Opposing roles of JNK1/2 and p38α MAP kinases
    Lal, Hind; Verma, Suresh K; Golden, Honey B ... Journal of molecular and cellular cardiology, 2008, 2008-12-00, 2008-09-26, 20081200, Letnik: 45, Številka: 6
    Journal Article, Publication
    Recenzirano
    Odprti dostop

    Abstract The cardiac renin–angiotensin system (RAS) has been implicated in mediating myocyte hypertrophy, remodeling, and fibroblast proliferation in the hemodynamically overloaded heart. However, ...
Celotno besedilo
45.
  • JNK1 is required to preserv... JNK1 is required to preserve cardiac function in the early response to pressure overload
    Tachibana, Hideo; Perrino, Cinzia; Takaoka, Hideyuki ... Biochemical and biophysical research communications, 05/2006, Letnik: 343, Številka: 4
    Journal Article
    Recenzirano

    Cardiac stress consistently activates c-Jun NH2-terminal kinase (JNK) pathways, however the role of different members of the JNK family is unclear. In this study, we applied pressure overload (TAC) ...
Celotno besedilo
46.
  • Role of Hsp70 in regulation... Role of Hsp70 in regulation of stress-kinase JNK: implications in apoptosis and aging
    Gabai, Vladimir L; Meriin, Anatoli B; Yaglom, Julia A ... FEBS Letters, 1998, October 30, 1998, 1998-Oct-30, 1998-10-30, 19981030, Letnik: 438, Številka: 1
    Book Review, Journal Article
    Recenzirano
    Odprti dostop

    Cell protection from stresses by the major heat shock protein Hsp72 was previously attributed to its ability to prevent aggregation and to accelerate refolding of damaged proteins. This repair ...
Celotno besedilo
47.
  • Atrial natriuretic peptide ... Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1
    Hayashi, Doubun; Kudoh, Sumiyo; Shiojima, Ichiro ... Biochemical and biophysical research communications, 2004, 2004-Sep-10, 2004-09-00, 20040910, Letnik: 322, Številka: 1
    Journal Article
    Recenzirano

    Cardiac hypertrophy is formed in response to hemodynamic overload. Although a variety of factors such as catecholamines, angiotensin II (AngII), and endothelin-1 (ET-1) have been reported to induce ...
Celotno besedilo
48.
  • GADD45B inhibits MKK7-induc... GADD45B inhibits MKK7-induced cardiac hypertrophy and the polymorphisms of GADD45B is associated with inter-ventricular septum hypertrophy
    Wang, Jianwei; Wang, Hu; Chen, Jingzhou ... Biochemical and biophysical research communications, 2008, 2008-Aug-08, 2008-08-00, 20080808, Letnik: 372, Številka: 4
    Journal Article
    Recenzirano

    Mitogen-activated protein kinase kinase 7 (MKK7) induces cardiac hypertrophy by activating the c-Juns NH2-terminal kinases (JNK). It has been reported that growth arrest and DNA-damage-inducible beta ...
Celotno besedilo
49.
  • Protein kinase C activation... Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells[S]
    Vargas, Noelle B; Brewer, Brandy Y; Rogers, Terry B ... Journal of lipid research, March 2009, 2009-Mar, 2009-03-00, 20090301, Letnik: 50, Številka: 3
    Journal Article
    Recenzirano
    Odprti dostop

    LDL is the most abundant cholesterol transport vehicle in plasma and a major prognostic indicator of atherosclerosis. Hepatic LDL receptors limit circulating LDL levels, since cholesterol ...
Celotno besedilo
50.
  • Crystal structure of JNK3: ... Crystal structure of JNK3: a kinase implicated in neuronal apoptosis
    Xie, Xiaoling; Gu, Yong; Fox, Ted ... Structure (London), 1998, 1998-Aug-15, 1998-08-00, 19980815, 1998-08-01, Letnik: 6, Številka: 8
    Journal Article
    Recenzirano
    Odprti dostop

    Background: The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein (MAP) kinase family, and regulate signal transduction in response to environmental stress. Activation and ...
Celotno besedilo
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